Objetives : This study was done to evaluate the antiallegic effect of medicinal acupuncture solution of Acanthopanax senticosus(Rupr. et Maoim;abbreviated as ASMA), studies were done experimentally.
Methods : For this aim MTT assay, anaphylaxis reaction, DTH, histamine release, IgE production and vascular permability was evaluated.
Results : ASMA didn´t show an effective cytotoxicity on the moase lung fibroblast. It insignifcantiy suppressed histamine release from mast cells induced by compound 48/80, while it significantly reduced IgE production and SRBC-chailenged DTH(Delayed type hypersensitivity). ASMA effectively suppressed anaphylactic reaction induced by compound 48/80. However, it didn´t inhibit vascular permeability and contact dermatitis significantly.
Conclusion:Medicinal acupucture solution had antialletgic effects.
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